THE ROLE OF PLANTS IN THE TREATMENT OF DISEASES CAUSED BY MICRO-ORGANISMS BASED IN THE NATURAL PRODUCTS (pure and applied chemistry)
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- NGN 5000
ABSTRACT
This study was carried out on the role of plants in the treatment of diseases caused by micro-organisms based in the natural products. The study was specifically carried out to determine the antibacterial effect of P. amarus and P. niruri, and determine the anti fungal effect of P. amarus and P. niruri. In the course of this study, Fresh leaves of Phyllantus amarus and Phyllantus niruri were collected at the University of Calabar staff village. the dried leaves were blended to fine powder using a manual blended (F No 4 Quaker City, Mill Philadelphia PA.U.S.A F8). and batch extraction was carried out on the material. The extracts were evaluated for antimicrobial activities against the following micro organisms (bacteria and fungi). the organisms used in the study were micro organisms gotten from University of Calabar Teaching Hospital (UCTH) microbiology laboratory. While Mueller Hinton Agar was used for testing antimicrobial susceptibilities using the disk diffusion method. The result of the study indicated that the ethanolic leaf extract of Phyllantus niruri was more active than that of Phyllantus amarus. The ethanolic leaf extract of Phyllantus niruri showed good inhibitory properties on the bacteria: E. coli, klebsiella pneumonia, Streptococas species, Bacillus species, Salmonella typhi, Staphylococcus aureus, Pseudomonas aeroginosa. For fungi, the ethanolic leaf extract of Phyllantus niruri was more active against Candida ablican and Penicilium species. Inline with the discoveries, the researcher recommends that Phyllantus amarus and Phyllantus niruri are important plants from medicinal point of view and can be potent candidates for further in vivo bioassays which could lead to the development of new drugs.
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